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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14069 | A-3 hydrochloride | CaMK , Casein Kinase , PKA , PKC | |
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv... | |||
T9881 | Benzoquinamide hydrochloride | 3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride | Others |
Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic agent and increases intra-arterial pressure due to the incre... | |||
T2287 | PIK-75 hydrochloride | PIK-75 HCl,PIK-75 | Apoptosis , DNA-PK , PI3K |
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays. | |||
T35526 | PI3-Kinase α Inhibitor 2 (hydrochloride) | PI3-Kinase α Inhibitor 2 (hydrochloride) | |
PI3-Kinase α Inhibitor 2 (hydrochloride) is a PI3-Kinase α inhibitor. | |||
T5978 | 2,3-Diaminopropionic acid hydrochloride | 3-Amino-L-alanine hydrochloride | Others |
2,3-Diaminopropionic acid hydrochloride (3-Amino-L-alanine hydrochloride) is a competitive cystathionase(CTH) inhibitor. | |||
T5683 | (2R,3S)-3-Phenylisoserine hydrochloride | Others | |
"(2R,3S)-3-Phenylisoserine hydrochloride serves as a pharmaceutical intermediate." | |||
T12906 | SI-2 hydrochloride | EPH 116 hydrochloride | Src |
SI-2 hydrochloride (EPH 116 hydrochloride) is a highly promising inhibitor of SRC-3 SMI: SRC-3 (PPI)(IC50 values of 3-20 nM for breast cancer cell death), with acceptable oral availability. | |||
T11188L | Emixustat hydrochloride | ACU-4429 hydrochloride | Others |
Emixustat hydrochloride (ACU-4429 hydrochloride) strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator. | |||
T61972 | Pomaglumetad methionil hydrochloride | LY2140023 hydrochloride | GluR |
Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride (LY2140023 hy... | |||
T4710 | 3-Methoxytyramine hydrochloride | 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride) | Others , Endogenous Metabolite , Drug Metabolite |
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human br... | |||
T10394L | ATB107 hydrochloride | ATB107 hydrochloride(455325-51-6 Free base) | Others |
ATB107 hydrochloride is a novel and potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM. | |||
T4234 | HJC0152 hydrochloride | HJC0152 | Apoptosis , STAT |
HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor. | |||
T8494 | NS-3-008 hydrochloride | NS-3-008 HCl | Others |
NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM). | |||
T40031 | Thalidomide-O-C6-NH2 hydrochloride | 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linker conjugate. | |||
T22638 | CBiPES hydrochloride | CBiPES HCl | GluR |
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used ... | |||
T12930 | SKF89976A hydrochloride | d,l-SKF89976A hydrochloride | GABA Receptor |
SKF89976A hydrochloride (d,l-SKF89976A hydrochloride) is a selective inhibitor GABA transporter such as GAT-1 (IC50s = 0.28 μM), GAT-2 (IC50s = 137.34 μM) and GAT-3(IC50s = 202.8 μM) in CHO cells. | |||
T11638 | Ilorasertib hydrochloride | ABT-348 hydrochloride | Aurora Kinase |
Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s: 1 nM, 7 nM, 120 nM). It also suppresses RET tyrosine kinase,... | |||
T4755 | 2,3-Diaminopropanoic acid hydrochloride | DL-2,3-Diaminopropionic acid monohydroch,3-Amino-DL-alanine monohydrochloride | Others , Endogenous Metabolite |
2,3-Diaminopropanoic acid hydrochloride (3-Amino-DL-alanine monohydrochloride) is an amino acid amide used as a substrate for studying the action of aminopeptidase enzyme. | |||
T1173 | Tropisetron hydrochloride | SDZ-ICS 930,Tropisetron HCl,ICS 205-930 | 5-HT Receptor |
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activ... | |||
T8639 | Phenibut (hydrochloride) | 3-Amino-4-phenylbutyric acid hydrochloride | GABA Receptor |
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptor... |